Hi,
I've just got this game and played through the first 40-45 minutes of it. I do all the vault part without any problem, up to the point where I have to get out of it.
I approach the dead scientist and loot the pip-boy from his corpse then, I use the console and see the small cut scene of my character plugging the pip-boy in the control panel, the glass cover of the red button lifting up and my character punching the button.

Sirens start blaring but that's about it, I can hear something moving down from behind the door (I guess it's the elevator I used to get in) but the door won't open. I went on to look at some playthrough videos on youtube and saw what it should happen, in their case after the character presses the red button, the room darkens and the big actuator over the catwalk starts to move to open the door, in my case only the sirens start, the red flashlights don't come up and the door stays firmly shut. I've tried to reinstall the game and, delete every save but had no success. Anyone experienced this bug and got a workaround?