I've been thinking about this for a little while, and being a long term can of the series, I know Bethesda is known for surprising us. My proposition for the next game is Akavir.

How it happens is between Skyrim and Exodus, The Aldmeri Dominion goes on the war march again deactivating the last few remaining pillars. One will remain active, and only one. We all know Nirn would dissolve into Oblivion given all the towers deactivate, but no one knows if only one stands what would happen. I believe Nirn has a defense mechanism by the Gods that will make Tamriel an inhospitable Hell. Members of the ten remaining sentient races must hurry and flee to Akavir. I haven't developed a plot, but A move this bold would make the game legendary.

Now, I brace myself for the hate storm. Have at you. Discuss.

I'm not going to hate it and I also hope to see akavir but I'm pretty sure that they'll do game out of some other region of Tamriel.

Don't worry, the moderators will lock this down before the hate storm gets here.

Probably. Better stay braced though, just in case.

http://www.gamesas.com/topic/1419943-tes-vi-location-and-setting-official-speculation-thread-4/