I can't think of anything possible though :/ I would of wanted a MQ that wasn't BANG Akatsoh the dragon sends you on a mission to assasinate Person X and save the whole world because the dragons were fighting some people :l
Don't get me wrong, I understand your point, and that would have been a good MQ if it was possible.
I'd like to see a working economy. In Oblivion there was literally not a single working mine. Every mine in Cyrodiil is abandoned? That makes sense... How do they make money if they import everything in the province?
I'd like to see varieties of mines, from iron to special native Skyrim mines. Perhaps there could be something similar to Stahlrim (though not exactly the same, of course).
I'd like it if there where more guilds. Assuming we'll be able to mine and create our own armour (there's so many suggestions about it), I'd like to see a miner's guild, with an underground mine, reserved for members, and a smithing guild, where I can learn to create different types of armour.
I would be able to mine 5 lumps of iron ore, and smelt it in a smelter, and then find an anvil, and hammer at the metal until I have a pair of iron boots. I would then have, say, 2 lumps of metal left, and would be able to create a pair of gauntlets.
I would also be able to mix different ores together to form different metals. I could, for example, smelt together some iron and coal and make steel.
It'd also be good to be able to add magical items to the mix. If I have an enchanted amulet, and the enchantment would fit on the armour I'm making, I could infuse it with the armour with some sort of magical device, and have the enchantment on the armour.
EDIT:
There's often talk about the Khajiit's different forms. I don't think it's needed to have so much attention on one race. Sure, perhaps both a more Oblivion "human" form, and a more Morrowind "beast" form. But no more.
If only one, though, I'd like to see the beast form. There was a mod for Morrowind that lets beast races wear boots by removing the boot section. Surely this can't be hard for you to do, Bethesda?
And about voices, ALL NPC's should sound like they live and have grown up in thier homeland. It gives the races more individual personalities and it defines thier characters. Khajiit's should speak in broken sentences, and Dunmer should speak with chain smoker voices! You never see a Nord without his scottish accent...
I wouldn't prioritise the smaller aspects of lore over a good gameplay experience. Lore is massively important, but the gameplay is more so.
And I wouldn't want there to be a waste of resources on the extra voice actors for 3 NPC's that are native to the land...