So I'm thinking Elswyr maybe two hundred fifty years after the event of Skyrim. The empire is shattered and Elswyr is probably in danger of natural and political upheaval. You are a prisoner maybe on his way to face the recently corrupted Council of the Mane. Badlands, savannahs, mesas, arid deserts, jungles, marshes, and coastal paradises.
Also to note the glorious return of crossbows, throwing blades (retrievable), and long reach spears and poles, complex companion stoylines, crafting skills, open cities and levitation!
New features include hats, capes, domicile pets, fishing, playable instruments, aquarium/tarrarium designing, a breed of hot air balloon type contraptions, unscripted geological and cosmic events, holidays, 420,000 lines of dialogue, piercing/tattoo parlors, and a free floating fleet of marine vehicle to populate the coasal harbors, fishing villages, and surrounding waters (Including an ancient Dwemer submarine you get to revive in a quest for the "fighter's guild" war against the Mane's secret police force.
Or it could be Valenwood or Summerset Isle or Highrock... what are your predictions?