It might be good to gather people's hardware specs for Bethesda and ourselves, to figure out what's going on.
If you're having texture loading issues post below with:
CPU (make, model, speed)
GPU (make, model, ram)
HDD (make, model, RPM)
RAM (make, model, speed)
MB (make, model)
Your game settings.
A DX Diag in spoiler tags.
This was brought to my attention when my Pipboy and other in-game textures weren't loading and my load times tripled, and it was because Avast decided to do a scan, taking up resources on my 7200rpm WD hard drive. If I was running the game off an SSD that probably wouldn't haven't affected me.