Or to boil it down, is it too easy or too hard to kill stuff, including you?
I think it is challenging enough to kill things at early levels, and it gets somewhat easier at higher levels. Like it should. My character has died at level 1, 2, 4, 6, 10, 14, 22, 26 and once time at level 30.
I don't feel that you should ever be able to one shot a high level anything, man, beast or machine.
I want the game to continue to challenge me at max level and gear, not have easy mode turned on.
At early levels, a one shot should rarely kill anything. At higher levels, one shot kills should happen more often, but mainly only head shots as expected. However, I put a 45-70 or a 50 Cal in someone, they better die if the shot hit a torso or head. Assuming of course DT did not get in the way with some of the armors.
I don't want the game to increase difficulty as I get better. I want the game to give me areas that I should not go to until I am ready, but other areas that I struggled through as I was starting out, should be relatively easier when I get back to them. Geckoes at the Goodsprings Source need to be weak little nothings when I am at level 10, but they should challenge me at level 1. Like they do in this game.
Pu the diffculty up if you want a challenge, but one shotting anyone is kinda boring.
Depends on who or what I'm shooting. A Bark Scorpion better not give me any problems once I reach level 5 to 10, but Giant Rad Scorpions still need to give me pause. Again, at level 20, those get easy and then it is Deathclaws that give me pause. I want to bask in some relative omnipotence as I go through the game, but still be humbled by some things or areas I come across.
Edit: in other words, no, I don't think all weapons should be able to do all things to all creatures.
Exactly, if I am using the right weapon, I should have success. If I am under-equiped, then I need to pay for that mistake, either by blowing through a lot of ammo, or stimpacks, or having to load an earlier save. If I have the right weapon and skills for the situation, that I spent the game developing or acquiring, I better get some easy kills on some enemies. But not all of them.