I posted something in response to this in another thread, but could not locate it so I'm going to have to piece it together again. Anyway, people keep looking at the short term effects of the Enclaves genocidal like strategies. Yes, they are not good, and yes lot's of people will die, but your not looking at the long term effects. So will look at the NCR's plan, and the Enclaves:
Let's say the NCR continues trying to expand. Clearly they are not ready to expand and their methods are creating enemies, but let's just assume they're capable of forming a new government. They will have to send out countless soldiers to every location in the United States to eliminate the threat of feral ghouls, super mutants, and other horrific creatures. We have no idea what most of the United States is like and there could be far worse dangers then we know of. These troops will be in short supply to enforce the government/towns they set up because they will be out getting themselves KILLED trying to eliminate Deathclaws and the like. On-top of this, radiation will still be present and all the people exposed to it WILL SUFFER FROM RADIATION POISONING. When your character gets radiation poisoning in the game it is a relatively benign danger, but in real life it is absolutely horrific. These people will suffer from extreme pain, their skin will peel off, and they will die (or I guess turn into a ghoul in Fallout lore). If they don't die during the radiation poisoning, but have kids while they are poisoned, then their kids will suffer from debilitating mutation's because radiation passes down after altering your DNA (see Point Lookout).
Now let's look at the Enclave's plan. They kill everyone that suffers from some sort of mutation (even the most basic, so basically everyone but the Enclave). OMG THEY ARE KILLINZ ALL THE PEOPLZ? Yes, but heres a question: Would you rather die a slow, painful death with your kids being born with deformities and your skin peeling off, or would you rather die quicker from a virus? This virus would not only do that, but it would eliminate the threat of all Super Mutants, Deathclaws, feral ghouls, Radscorpions, etc. The Enclave will not have to worry about their settlements being overrun by creatures hell bent on killing everything in their site. Instead, they will be able to expand without their families fearing traveling past the next mountain corner where a pack of Deathclaws are waiting to rip them apart.
So is the Enclave's plan genocidal? Yes, I'm not going to lie, it is very devastating. However, the long term effects could be much better than having people sit on their asses, farm, and die from radiation/mutants. Now people (well technically the Enclave) could rebuild the wasteland with a government that doesn't have it's forces stretched thing defending everyone, and mutants screwing up everything they accomplish. They would be able to devote there time to establishing communities, eliminating any threats of radiation left over, and rebuild.
Okay but that plan is only good for the Enclave.
When did the radiation poisoning affect only the NCR that would happen to the Enclave too. Also do the people seem to care, they knwo no other alternative to living life ina wasteland adn I am sure they would rather live. Why do you need to force out every Deathclaw adn aberation, you dont only ones in the immediate area, people in tiems past did not do all this.
The Enclaves plan again does not kill mutants only humans.
Also what si wrong with people sitting on theri asses on in their farms, adn living a life rebuildign and eventually retaking the entire world. Eventually the Enclave would splinter anyways, thats just human nature. Yah their plan is great idea, I am not denying that, Im just saying that IMO it is nto really a great idea, ti si but it is not, get it.