This game killed my console last night, got hard freeze, then black screen followed by 3 beeps & flashing red light.
Now when i try to turn my PS3 on i get the usual blue green light, followed by single yellow flash & red flashing after.
I'll be getting a new console & i won't playing any Bethesda games on it
Well, what you described is the PS3 version of the Red Ring Of Death.
This can be caused by anything from turning off your PS3 via the back switch and corrupting the OS to hardware failure to anything that would prevent the system's OS from running.
In other words, you bricked it.
I have freezing in Fallout:NV, but I eject the disc and then press the button on the front to do a soft reset to allow the BIOS to take over.
I have not had any serious issues outside of that.