I think the thing is is that some people have a sense of morality and will abide, some know right and wrong but will put their morales aside for an indulgance of human pleasure, then there are people whos compass just plain fell out their pocket and broke. Nipton is the second group.
That's always the age old debate about human nature, says a lot about a person if they think most people are basically good, basically selfish or basically predatory. Especially since most sociopaths lack the empathy to imagine most people are not like them: they tend to have very mercenary, pessimistic views of humanity.
But on the original topic. I did my first two playthroughs as high-karma "paladin" types. Not BoS paladin but the "suffer no evil to live" lawful-good militant type of Paladin.
He was a powder ganger, he got a laser to the forhead.
On my legion playthrough I beat him to a pulp too, but that's because I was playing low-karma and had the kind of character that kicked puppies and peed on orphans, she'd have done it just to see what the inside of his brain pan looked like for fun.