Question is in the topic.

Are the existing containers in the presidential suite safe to leave items in?

Should be; i always stick with Novac myself, but since the Suite is yours you can store whatever i remember a time when i was in there and i just had smoked House when the room loaded there was 2 Khans just chillen in there i was like O_o

Novac? Can you get a home in Novac? I haven't had time to play this game much. Haven't even finished it once yet and I picked up my pre order the day of release... sad really.

It's safe in the sense that your stuff won't randomly disappear from boxes (unless you overload them), but if you direct companions there they might take some items from time to time.

Talk to Jeannie May Crawford at the Dino Dee Lite Motel, and she'll rent you a room for 100 caps. Once you pay her for the room, it's yours to keep for the rest of the game. Your room is the first one behind the lobby upstairs.

better off with novac really.by the time you walked through all the gates,through the building to the room and back again you could already be at your next destination with novac.sure it looks nicer but think about walkin all that way over and over its gonna get old real quick.plus the company is a bit boring up there