Well, there can't really.
With how long running series adapt and change over time, with the newest info always overriding the old, there really cant be mistakes, just NPCs who are, as real people are, misinformed.
-Fallout 1 said all ghouls came from Necropolis, this was proven wrong in Tactics, 3, NV, and 4.
-Some scientist in Fallout 1 said its impossible for animals to have mutated solely due to radiation, Tim Cain, Fo3, NV, and 4, all showed otherwise.
-Older Fallout's said that ghoulification took place over a long period of time, but Fallout 3 and NV show it can happen instantly.
-Older Elder scrolls games said Tiber Septim was a Nord, from Atmora, and became Talos, all of this was disproved later.
However, that does not mean any of the previous statements were a "mistake", those people did actually belive those things. All it shows is that the people who made them were misinformed, just like people tend to be.
Its even mentioned in Fallout 2 that Jet was made using a process from before the war.
http://fallout.gamepedia.com/Jet
Its not a far stretch to say that someone realized this could be used as a drug, and actually made one, and that Myron was doing nothing but recreating something from before the war.