I find it short sighted of them to think that all they have to do is remove man. Isn't it plausible that the Sload and/or Akaviri races are worshipping, in sufficient numbers another god/aspect of the same god that does what Talos does to keep that Wheel of the Convention fortified.
I have an image of the last man being executed, the Thalmor trying to put whatever plan they will use to unmake the world into action, it failing, leaving them scratching their heads.
Or them getting the power to unmake the world (Eye of Magnus) after removing the possibility of man, and all they succeed in doing is basically eating this Kalpa themselves because their souls are still bound to that plane.
Probably mild to vast speculation on my part, but thats part of the fun :disguise: