I'd like for the cities to be maybe twice the size of the Imperial City and without such divided sections. The IC always seemed slightly claustrophobic to me because each district was in its own cell. If the cities are as big as I hope for them to be, they need to have a nice flow to them or else the increase in size won't matter too much.
And I really hope they actually do something with the space. In the IC, they really wasted space by with the Arboretum. If there is going to be a sort of "park" or "garden" space in a city, it should actually feel like it. The Arboretum was just an open space with a path leading to the Arcane University. And the Elven Gardens district was basically an extension of the Talos Plaza district.
Anyway, I just am excited for the cities.