I think that one of the worst things that COULD happen is the lack of voice actors like in oblivion. Yeah the Patric Stewart and Sean Bean was pretty cool but I would have sacrificed their price for a larger amount of Lower profile voice actors. Another thing would be cities that don't "regenerate" after dragon attacks. I don't want to loose quest givers and have ghost towns and I don't want to see broken buildings weeks after the disaster when the cities looks so cool, Kavtch the 2nd would be for me, game breaking.
I think we all know that the game isn't going to be "Dumbed Down" adding in a more complex combat system and the introduction of Trade skills to name a couple.
Someone above spoke about Black Powder Weapons- HELL NO! IMO The idea of Guns in Fantasy Steal the magic away from it, and with Magic why on earth would you make a gun, its unreliable less diverse, and for those not so magically gifted a bow is a lot cooler (Crossbows would be cool as well though) . Also Musketeers are LAME
and if I wanted to Play guns I'd hop on Bad Company 2.
As for culture Each Town looks vastly different and there will be bards from what I've seen so far, Vastly Superior to that of Oblivion where the deepest it went was statues with stories, building models and that meeting Tree in Chorrol.
Which leads me to:
What Has Been Confirmed That I Don't Really Like The Sound Of. Firstly, Being able to fast travel from the main map. In an article about the menus, it stated that you can in fact zoom out and inspect different parts of the map, which sound quite cool, but it did mention fast traveling in the map section. Hmm more oblivion style fast travel
, I think that Morrowind style fast travel was great but I hated oblivions, and yes people say you don't have to use it but you always end up using it. And finally level locking on dungeons. When I'm level 30 and and I've Cleared Most Dungeons in the game I'm gonna to want to go back and visit old ones but it wont be worth while unless they creatures and loot are level 5.