Eg with radeon pro I can enable FXAA ultra (x4), SMAA ultra (x4) MLAA (??) and 16xAA. My crossfire 7970s can barely reach 60 fps with dynamic vsync enabled. Cards were running quite hot as well 80oC. I think I can smell smoke, so not sure if its good for the graphics cards lol.
Game looks bloody amazing but would be nice maybe if I didn't need them all enabled.