Only the largest and most complete mod in all existance: http://www.gamesas.com/index.php?/topic/1108040-relz-oscuros-oblivion-overhaul-133/
. Basically it's a massive overhaul that makes the game much more static and makes the level of your enemies dependant on where they are and not what your level is. It makes the game much more challenging, especially at low levels. Might I also recommend MMM which works great with OOO- it adds loads more monsters to add the variation vanilla Oblivion was missing and the tougher enemies OOO needs in the wilder areas of Cyrodiil.