After beating the game twice (Institute ending and Minutemen ending), and watching the other two on Youtube, I'm left with the following question: How can any "good" character justify going against the Institute?
Your options are:
1. Work with the Institute to make their technology beneficial to the people of the Commonwealth, while taking huge steps to change their image and communicate positively with settlers. Violence is always the last resort.
2. Work with the Minutemen to destroy the Institute because a handful of it's researchers abused their incredible technology, destroying mankind's best hope for a future because the general population doesn't understand it.
3. Claim the Institute's tech for the Brotherhood, who have essentially engaged in a hostile takeover of the wasteland. Bomb the hell out of everyone else to steal their tech.
4. Join the Railroad in their quest to kill lots of real people in exchange for helping out fake people. Take zero responsibility if those fake people go crazy. Kill the real people who create those fake people. Have no further plans for the future.
As the leader of the Institute, your character has the power to utilize all of the organization's technology for the betterment of mankind while simultaneously putting an end to the small number of morally gray experiments they engage in. You could easily create an Institute where Synths have freedom (there are scientists in Robotics who seem to want this even under Father's rule), and where kidnappings (which are already exceedingly rare and conducted only by a small facet of the group) are abolished entirely.
The sad thing is, the average Commonwealth citizen still sees the Institute as evil, largely due to unfounded rumors and exaggerated stories that seem to have all spun out of one or two small-scale tragedies.
Even close allies like Nick and Piper refuse to see the Institute as good, seemingly ignoring the fact that you, their friend/savior/lover, are put in charge of it. These people will only agree with you if you choose to indulge them in their ignorance, burning the equivalent of the Library of Alexandria just because people are suspicious and uninformed.
So again, I'll ask: How can any "good" character justify going against the Institute?