It'd be best to disable them though, due to inherent issues with autosaving instead of using "hard" saves.
That's why I'm using ASU, it's my backup. I always make it a point to delete one save each session as well so there's a rotation of new saves. Frankly, after hearing about this same issue with Oblivion, I think the problems are overblown. I've always used auto-saves with that game and rarely had a problem. If I did, I had a Streamsave as a backup. I was using hard saves with this game until just recently, since I thought there was a problem with them in my game. But it turns out it was your CASM mod. After awhile it was causing absurdly long delays in my game, like up to a minute. Since using just the game's auto saves and ASU, I haven't any problems with that, and I'm greatly enjoying the convenience of not having to open up my menu every few minutes. As for the message, I did find a work around. I removed the text message by adding a single space instead, then told the DarN UI not to show the message brackets. So no more Autosaving messages.
It's ironic really. The reason why I wanted to have an auto-saver mod running was because my game has a tendency to crash every so often. But now that I have ASU set up and Auto-Save working, that rarely happens now. It's been hours since my game has crashed. I'm wondering if having my Auto-Save shut off was actually causing problems for me, since my crashes quite often occurred as I was transitioning. Perhaps the game was expecting to do an Auto-Save but got confused because it wasn't allowed to.