oh yes. be sure to get all the modding utilities. in addition to the above, get archive invalidation invalidated. personally i use garybash for load order and bashed patch. BOSS-F, for automatically ordering your mods too.
invalidation comes with FOMM [fallout mod manager], but i think i might have to try garybash and those others.
and another thing you may want to get the unofficial patch. it fixes things in the game and DLCs that beth didnt.
and if those dont suit your needs.. get the G.E.C.K which can be found on the fallout home page.
good luck with mods!