Spoilers.
Vault 81. Dr. Penske. If you eat the special Mutfruit she gives you, she'll then ask you for a favor. She asks you to bring her bags of fertilizer and she offers you 25 caps per bag, non-negotiable. I agreed. I already had several bags in my inventory. However, speaking to her again just makes her give you her normal dialogue run-down. She mutters to herself, talks about her crops, etc. In all THREE of my different save files, I have never once been able to complete this turn-in quest. It doesn't give me a quest in the Pip-Boy, there is no dialogue option, even after waiting a full day and coming back you cannot give her the fertilizer. I have tried waiting until all Vault 81 quests were completed and coming back. I have tried doing it before doing any other Vault 81 quests. I have tried reloading earlier saves. I have tried every possible thing I can think of.
Is this part of the game Bethesda meant to turn into a turn-in quest, but never finished it, or simply FORGOT about it? Seriously. FIX. THIS.