Mr. burke is the first NPC you'll meet in lonesome road :disguise:
O yes, but he hates those dang ghouls, so you see a bunch of ghouls outside a military base, holding boycott signs reading, "We not crazed, we just High".
Then Burke wants you to nuke the divide, and Megaton!!!
This being cause Burke gave the beacon, but the idiot lone wanderer went into D.C and died, loosing the beacon. Only to find out, he just tossed the Beacon and ignored Burk's offer all together.