Hi. This is my first post here. I am looking for help with the issue like in the title.

Each time I talk to Lucullus in Cottonwood Cove and take an option to travel to Fortification Hill to meet Caesar the game crashes to desktop.

I thought that maybe autosave fails to work properly but disabling Autosave on travel doesn't help.

So I can't progress in main quests.

I found some trails on various sites that it's an issue happening to others, but can't find any solution.

My game is of course original bought in a shop, then I believe extensively patched via steam (took hours to download data when I first installed the game), with all the DLCs also fully legal (I already finished all addons without major issues and now came back to main plot). I experienced occasional crashes throughout all play but never was it that permanent - usualy loading a save and trying again was enough to progress.

Can anyone advise how to solve this problem? Thank you in advance.

Do you have any followers with you? If so, dismiss them. You may even try the companion dismissal terminal at Gun Runners or at the Lucky38 if you don't think you have any companions.

Does this happen with an even earlier save?

Do you have any mods?

Sometimes waiting in place for 73 hours will clear up any script hangs that can cause a crash on going to a cell.