Mr. House always wins. i go with him because at the moment, he is indeed the best thing for this world for now. Freeside i may not have loved the greatest, but i like it because i actually have memories of the area (like the guy who waves you to the alley then tries to kill you), Gannon was my favorite, even over boone, mainly because of his deep and intertwined story, as well as his comical relief
*points gun* "um...what's up?"
best faction in my opinion was the kings, but other than that, the securitrons were a favorite. so cold. so orderly. so...efficient... >:)
quoting house: "you needn't be afraid of me, it's my securitrons that are going to kill you."
EDIT: and in my opinion, the worst voice acting in the entire game was the fiend that greeted you in vault 3