I'd recommend you follow the PS3 tech forums on this game. Bethesda claims they'll fix the problems plaguing the PS3, but for now, I'm sure the game would be perfect if you stick under 60 hours total gameplay or so.
Ha ha 60 hours! I'm at 140 and haven't even toured the whole world, seen 3 of the major cities, finished the main story line, or hit 100 in anything but blacksmithing. I also still have a log full of unfinished quests waiting for me. Not sure how anyone could do much in 60 hours. This game is massively huge.