Considering you have checkboxes on the filter window, it should be trivial to change the dropdowns to checkboxes.
And to further optimize the Filter window itself, you can cram the checkboxes in the dropdown list itself. That way we won't have bloated window with nothing but checkboxes.
And I will provide an example:
Let's say that I do not like Instant Action, but like TIA and CS, I can then deselect IA and get every game mode, but IA. Or don't like Sanctuary and Pier17, but prefer any other map. Instead of like going back, changing the settings and redoing the scan every single time for every single game mode and/or map.