Workaround 1:
1) Clear your system cache to delete the patch.
2) Start Fallout and make sure you select NO when it asks you to update (stay signed out).
3) Load up a save, fast travel or walk to a different location (ex. Primm), and then create a fresh save.
4) Exit to the dashboard, sign in to Live, and start Fallout.
5) Download the update and load up the fresh save.
Thread: http://www.gamesas.com/index.php?/topic/1125764-update-released-yay/
Workaround 2:
1) Start Fallout and load the save you want to use.
2) Randomly switch guns, hip fire, switch guns again, and hip fire.
3) That's all you should have to do.
Thread: http://www.gamesas.com/index.php?/topic/1125797-update-causes-repeatable-vats-crash/
Please post which one of these worked for you. If you still can't get around the bug, please post the location that you saved from when you applied the patch. It may not be only Nipton. It may not even be the location causing the problem, but the location is always Nipton so far from what I've seen.
Helped:
http://www.gamespot.com/xbox360/rpg/falloutnewvegas/show_msgs.php?topic_id=m-1-56853374&pid=959557