But the lone wanderer has Hellfire Armor which is the most advanced post war armor available and with the help of his Lincolns repeater and the Mysterious Stranger (who does like 9000 DMG).
Not even close to the protection of APA mk II in FO2.....
http://fallout.wikia.com/wiki/Enclave_Hellfire_armor
Total of 60 DR and +1 to str. (+1 STR in FO3 = 10 lbs of extra carrying weight)
Suit was 44 lbs. -34 net weight.
http://fallout.wikia.com/wiki/Advanced_power_armor_Mk_II_%28Fallout_2%29
18 DT and 60 DR +4 to Str. (Fallout 2 you get 25 lbs per point of Str. so suit gives you 100 lbs extra carry weight.)
Suit was 50 lbs. +50 lbs net weight.
APA mk 2 has over 60 DR in all damage categories...
plus we have weapons that can do http://fallout.wikia.com/wiki/File:VindicatorMinigunDamageReporting.png