I voted anti voice, but I do believe it wont matter that much. Ofcourse, that relies on other things, and for me it relies mostly on how linear the game plays out; How forced will start of the game be? The two games that I have replayed the most: New Vegas and Skyrim, both are rather unrestrictive in the start. You go through a short introduction without much conversations, and then you get somewhat left to yourself.
The voice used seems quite neutral, and as long as there isn't too much comments as you go through the world, will be unnoticable. About the lack of descriptions, I do agree that it svcks that they are so short and undescriptive. However, using a voiced protagonist, I think having full sentences written out and read before selecting the option, and then hearing it said, is a bit much. That would probably cause the voice to become more annoying, as it will repeat something you've already read.
I think there will be a sollution to this quite quickly, if not by release:
There will be subtitles available, meaning that the written text will be in the game. This could probably quite easily (?) be set as conversation options instead (mod?), leaving your character mute.
I also believe that there at times will be more dialog options than up to four. Based on pure speculation.
Kinda off topic:
Do you think it will be easy to edit the voices? Speed up/slow down, or edit the tone of the voice? I am no modder, nor programmer, but adding a code that plays the audio recorded by Bethesda in an edited way seems to be much easier than other stuff done. Also, adding variability to the voice is probably something that will be very sought after.