Well, personally I find it a slightly more fun experience to zoom in with a long night scope on a Hunting Rifle than plinking from the same distance with a pipe pistol. Somehow I think Bethesda does too, it's kind of the point of the game; to improve your character as time moves on. You're supposed to go; "wohoo, what a cool weapon, I can't ′wait to use it". Not; "Oh, dang it, a Combat Shotgun. Woe me, what ungodly fate has befallen me, I don't want this... thing".
Handicap myself I can do when I have beaten the game and like to fool around with silly builds and crazy quest solving. But not on my first play-through. Right now the game is too easy for me and there's nothing I can do about it.