It would seem that the Lone Wanderer, if he/she so chooses, can really mess with pretty much every organized religion in the Capital Wasteland...

1. The Church of Atom. A bunch of weirdos worshipping an undetonated atomic bomb. You can either blow them all up (not nice), or disarm the bomb in question (which is nice, but they might not appreciate it). Either way, it pretty much finishes them up.

2. Oasis. The people worship Harold/Bob/Herbert (despite his best efforts to get them to desist). You can kill him (in a nice way or a nasty way), which will pretty much end that.

3. The Church of St. Monica. Follows Roman Catholic traditions, but seems to focus more on St. Monica than anything else. Consists of one priest, who looks like he has one foot and several toes of the other in the grave, and an acolyte (his heir apparent). You can force the acolyte out of the priesthood by slipping Angela some ant pheromones. Ergo, once Father Clifford dies, the church goes with him.

Thoughts on the subject?

Yeah I have one... What is the point of this topic?

You can mess with people, so what?

Ok.