Im having this issue too, it's really annoying. Close to selling this game

Nothing works... It needs a patch I guess or the game is unplayable. I have noticed more and more players having the same issue.

We've implemented a fix for weapons locking up after completing the Reunions quest as part of today's http://www.gamesas.com/topic/1559864-welcome-to-the-steam-beta-update-forum/. The full update will roll out to PC, and then on consoles.