One of the funnier glitches I experianced while playing new vegas happened while I was meandering throughout the vast wasteland of new vegas when I heard the pitter patter of a deathclaw.
In the distance my last chance of survival appeared on the horizon, an abandoned subway tunnel. After franticly scrambling towards the subway tunnel entrance I made it to the door only to find it locked.
Using my leet lock picking skills I masterfully cracked the lock and opend the door to my salvation. Unfortunatly 12 foot tall dinosaurs know how to open doors and close them. After getting through the loading screen I got a pleasant suprise of a deathclaw face in my face. Dropping several F bombs at the stalker of a deathclaw about to take my life I managed to make it into the main tunnel of the subway.
Speeding down the subway triggering landmines and upsetting feral ghouls with deathclaw in fast pursuit. I found a door leading to a subsection of the subway perhaps another chance of escape? No the door to freedom is a lie! I ended up falling through the floor, falling for one minute, and finaly teleporting to a dead end of the tunnel with an impatient and upset deathclaw awaiting me.