"This is why the great crusades against lycanthropes led by those like (hunter's name) are ultimately futile, unless the families who carry this bloodline are exterminated as well."
And in Solshteim, when asked about werewolves, some people would say "I don't believe they exist. I mean I know they did at one point, but I've been told they have been hunted down to extinction"
So, lore is kind of vague on the popularity of werewolves and such. Does the Great Crusades against Lycanthropes have to do with their supposed extinction(Which we know it's not true since Bloodmoon had werewolves". And the time frame from "Daggerfall" to "Morrowind" was how long?