(This thread is not about discussing F4. So don't recommend http://www.gamesas.com/topic/1414088-fallout-4-speculation-suggestions-and-ideas-thread-90/ )

What do you think is up with the commonwealth, espescially the infamous institute?
It got referenced in both F3 and NV so let's speculate about it!

It develops androids.
Railroad no likes how they treat androids.
Some androids escape.
They hunt them down.
Institute is the ol' MIT.