My answer was: minimal, like:
uGridDistantTreeRange=15 (with respective change in Streamline 3.1 ini according to the readme)
uGridDistantCount=15 (with respective change in Streamline 3.1 ini according to the readme)
because increases FPS significantly
bBorderRegionsEnabled=0
Because some mods are outside Cyrodiil
[Fonts]
sfontfile_1=Data\Fonts\DarN_Ringbearer_22.fnt
sfontfile_2=Data\Fonts\DarN_LG_Kingthings_Petrock_14.fnt
sfontfile_3=Data\Fonts\DarN_LG_Kingthings_Petrock_18.fnt
sfontfile_4=Data\Fonts\DarN_Oblivion_28.fnt
SFontFile_5=Data\Fonts\Handwritten.fnt
Because I use Darnified UI 1.3.2
bSaveOnTravel=0
bSaveOnWait=0
bSaveOnRest=0
Because autosaves are corrupt
bAllowScreenShot=1
bMusicEnabled=0
Because I like the cool sounds by Bethesda and the mod-added ones.
Now, when I think about it I am sure there are safe things to change so that I can enjoy better video and better performance. Would like to improve water settings, video settings etc.
What could be your tip?