Ive been seeing this talk about Dead is Dead playthrus and this and that and I'd like to know what that means please.

Why didn't you check the threads then?

also it means if your character dies, its dead and you have to start over.

You die= New game

Question asked and answered. Some people find the gameplay more intense or immersive or whatever if the element of risk is there wherein if you character dies, you lose that character -delete it or simply never play it again, roll a new one.

I die too frequently in games for this to ever be a viable play style, but some people really get into it.