Having a good story and/or cast of characters is nice and all, but few RPGs actually pull either off well enough. Bethesda's games are NOT among those lucky few.
What things turn me off? Combat-heavy RPGs with horrible combat. Terribly-balanced RPGs where only one or a few options are even remotely feasible to succeed in the game. RPGs that are grind heavy and/or have excessively slow pace are also not my cup of tea.