I'm specifically asking if there are any outstanding new mods, be it graphical enhancements, levelled list muckamuck, or new quests and companions.
A precautionary tale for mod users: I had a quite comprehensively modded, bossed and bained installation that worked for about a month before it started to crumble under its own weight from ram related crashes. I think the straw that broke the camel's back was RAEVWD. Moral of the story being that you simply can't combine ALL the major npc, landscape, levelled list, quest, combat, texture and sundry other mods, no matter how carefully you order them. Your computer may be up to it (I had a decent 20+ fps), but Oblivion's poor engine just can't figure it out. :shrug: So pick and choose a bunch and save the rest for another playthrough.
Edit: and I'm sure RAEVWD works great so long as you're not a foolhardy s'wit like me!