This is hard. I want to make a magician/stealth hybrid, a male Khajiit struggling to learn magic that eventually becomes very good at it. I think it's going to be hard to choose how to spread out my perks. Choosing just four will be very difficult for me, but I'll try:
Sneak
Destruction
Illusion
Alchemy
It will probably turn out differently than that. I'll try to weed out the skills I will try not to use much for this character.
Frequent Focus:
Alteration
Destruction
Illusion
Restoration
Sneak
Lockpicking
Speechcraft (maybe)
Lesser focus:
Conjuration
Pickpocketing (maybe, but not on innocent people)
Crafting in order of priority:
Alchemy
Enchanting
Smithing (Will likely skip perks if I don't use the smithed stuff.)
It would help to add a recap of all the skills in the first post:
WARRIOR
-Archery
-Block
-Heavy Armor
-One-Handed
-Two-Handed
-Smithing
MAGE
-Alteration
-Conjuration
-Destruction
-Illusion
-Restoration
-Enchanting
THIEF
-Alchemy
-Light Armor
-Lockpicking
-Pickpocketing
-Sneak
-Speechcraft