What is a Synth?

-Part II-

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Since I loved the first thread, I just decided to start a second one. The premise of synthetic humans being created from advanced robots through new, improved AI processings into a humanoid form, used primarily as perfect avatars (? by Styles) and later gaining self-consciousness and escaping their creators and percieved captors, the Institute of the New England Commonwealth, is full of possibilities.

What do you think about how synths influenced the wasteland through their occurence? Is there a fundamental difference between even the most advanced android and a human?

Feel free to discuss.