Animal whisperer faction
I would like to suggest a DLC with a vast New York New England wilderness with few targets worth nuking and thus a few scattered wasteland areas I would like to have hundreds of small scattered pre war rural communities that have survived with their local light industries (including quarries, cement, concrete and mortar factories) and grown because of the farm and rural traditions of preparing for all foreseeable hard times.
From these communities I would like to see a Followers of the Apocalypse type Tinker faction grow that sends teams into the wasteland through their network to set up schools and clinics to help educate and raise the living standards of wasteland survivor communities. These schools encourage graduates to apprentice with their volunteers to help serve other survivors both local and ever further out, and maybe join their faction, if proven suitable.
A faction that trains tinkers to help communities modernize local technology to improve local farming, help recycle local scrap resources, rebuild or recycle buildings accordingly and build new ones (bullet resistant mortar and stone buildings along the perimeter of the town that invaders must pass between. The shooters don’t have to worry about their bullets penetrating if they fire on invaders between buildings, as buildings cover each other.) Maybe they help settle the nearest local wilderness.
I would like to suggest an animal whisperer faction of big cat, canine, canid (wolves and foxes, etc), and caniform (bear, eventually Yao Guai) handlers and owners who planned for their charges as well as themselves, and reached out to other members of their community to organize months before the war.
200 years later and many generations of breeding there is not much in any of these families of animals that cannot be a good loyal companion to someone who has trained themselves to work with these animals, (and no they cannot talk, but maybe you can mod such a “skin” on a Dogmeat frame, even a dog sized cub if you’ve wanted such a companion.)
I think the animal whisperer skill should work to keep wild animals, including Yao Guai possibly Death claw, from attacking you. I think it should be one of the skills you can learn in an established Tinker school from members of the animal whisperer faction.
I offer that if you can train a dog you would be encouraged to adopt a hatchling Death claw as an experienced whisperer can get them to bond so the Death claw will imprint on you and your dog as ducklings, goslings and such will the first person or animal they see after hatching (provided it doesn’t kill and eat them.)
Whisperers have done this for generations now, and bred even more generations of Death claw to be loyal pack members to their adopted family.
Communities like such families because while Death claws cannot bark with dogs they can howl with them (sounds a lot like large boulders grinding against each other), and the grief howls of a dog and Death claw if you have killed one of their beloved has an especially bowel loosening effect on those who have incurred their wrath. If you want to live, and you have the time to relieve yourself before you leave, you should probably just start running and throwing away everything that will slow you down.
Especially if a neighborhood full of sympathetic paws and claws are coming with them, after you and yours. You will have a long way to run; reeking of sweat, urine, feces and fear and the only thing that might help you against a pack of maybe a couple hundred armored death claws and who knows how many armored dogs, and wolves of war trying to keep up, is maybe a couple thousand slower runners behind you, and hundreds more falling behind from up ahead.
Given how hard it is to get a few hundred to head into what is probably a vast wasteland from which no one anyone you can talk too claims to have returned, How big a raiding party (from which no one will return,) did you go up with? Now what made this place worth attacking in the first place?
Climbing a tree to where an advlt weights too much to follow does little good against the juveniles who are as arboreal as a monkey, one youth half your size and weight can kill you quick with one paw, and it had better not be wearing bullet resistant armor when it catches up to you because it is going to be fast moving, very maneuverable and probably not alone. Even if you have an energy pistol, it is probably best to turn it on yourself, if you have the time.