So what, you throw bottles at them? Plant chokeberries into their inventory?
No but like I take a bunch of non combative majors like Mercantile and Speachcraft, Armorer and Alchemy. Which are generally thought to lead to leveling nightmares if you take any of them as a major, I use all 4 of them together.
Then I rely heavily on poisons, and buffs whereas most people use alchemy just for healing and magicka. Most people view Alchemy as a supporting skill, but its actually the skill I base my characters around. I use it for everything, whereas others would use swords, archery, or destruction. I will use whatever is handy but buff the hell out of it with poisons, or skill and attribute fortifications. My characters take steriods.
Then I play Orc, Altmer-Apprentice, and Imperial characters. Orcs are the least used in every pole Ive seen, Altmer-Apprentice is considered High RISK, and Imperials have social buffs rather than combative buffs, thus are thought to be less powerful.