No spoilers please, a simple you can keep going, soon, or you better start the others now will suffice.
Don't worry, you get a warning about it when it's to decide "Do I want to make them my enemy". Unless you attack them or say the wrong thing to a leader. Then you're basically screwed. And that could be anytime you're talking to them.
A clear one I hope and not like "settlement is under attack" ?
Oh, yeah, pretty darn clear. Message box that you have to hit "ok" and everything.