This is what I'd recommend as well, since both programs have functions that are very useful, I might even say essential, for players who intend to use lots of mods together. For things that either problem can do, I prefer Oblivion Mod Manager as its simpler to use, but Wrye Bash is good for the functions that are unique to it.
Being able to use OMODs is only one of many useful functions that OBMM offers, and in fact, I haven't downloaded all that many mods that are only available in OMOD format, often, there's either an OMOD or non-OMOD archive available, or, more often, they're distributed in "OMOD ready" archives, meaning that you can install them manually but converting them into OMODs is quite simple if you so choose, so more often than not, it seems that the OMOD format is a matter of convenience rather than necessity, still, even if you don't use OMODs, the other functions of the mod manager are also quite useful.