» Sat Jul 03, 2010 1:47 pm
(Particularly if you have a large screen and play on a large resolution), fix your UI. Use DARN or the other mod that I sadly forget that will make the font smaller and the game less annoying that way.
Look at the community compilation patch. You don't have to install the whole mod: so far, I haven't ran in to any bugs or annoyances with it so I'd say 'why not', but everyone's different. If you're spoiler phobic, I recommend just taking the whole thing... if you're not, then read up on the patches and mods included in it, and install what you feel you're need. Using Veronica? You'll want the fix for her leveling and for her quest. So on, so forth.
At that point, I'd start playing.
Then, add what you think you need. You mentioned perks and leveling- play first, and see how you're doing. Do you really, really, really want more perks? Then add the perk every level (although as said it does make the game much easier) and the various more perk packs. Do you find hardcoe too tame? Add a mod that ups the requirements. Are you annoyed with how guns work? Look at the various 'realism' mods for that. Want armor more worthwhile? Check Arwen's realism tweaks. Do you think you need MOAR FOLLOWERS? Grab a multi-follower mod. Find yourself leveling too fast? Then look at the cap removers, but only after giving it a spin.
You certainly don't have to complete your playthrough, or even play that long. After even an hour of play, you'll probably have an idea of what you want.