Strength is Melee and Carry weight
Perception is likely compass range and VATS accuracy
Endurance is Health and sprint duration
Charisma is speech
Intelligence is....EXP? Damn the mighty have fallen
Agility is sneak and AP
Luck is crit
But here's the thing: you start at 1 SPECIAL each and you only get 21 points.
For the first time ever, the average character will be a 4 in everything, rather than a 5+.
This leads me to suspect that 1's are viable, AKA, you can safely leave any stat at 1 and still be a totally viable character. In past Fallouts, dropping SPECIAL down could hurt, but here? It'll probably work fine.
So then...
What if I make a character that has no intention of using melee or VATS and I myself am patient about leveling up? I have no motivation to increase Strength, Perception, Intelligence or Agility. What's more, Charisma has always been a neglected stat, and my hunch says that hasn't changed. This means that wtf I should just pump Endurance and Luck to max for better HP and damage respectively. Viola. Best character build.
Am I missing something?