Not really, though. I don't think that's even possible, personally. Turn-based games rely on more than just making called shots a la VATS, after all, or making use of die rolls. It's more about having a discrete set of rules that allow you to weigh your options, with everyone working on a level playing field and having access to those same strategies.
For example, I could make a real-time version of Chess where all the pieces constantly move around in real time. That might even turn out to be a fun game in it's own right. But even if I then added a button that allowed me to pause the game and give orders - I'm just buying myself more time to strategize what's going to happen in the real-time game. A Grand Master Chess player would not be able to just adapt the same approach to a real-time Chess game - by changing the very foundation of the way the game functions, you're changing all the rules, thus changing all of the strategies.
This doesn't mean I think VATS "failed" at turn-based. I just don't think that was what the attempt was. I enjoy making use of VATS. It's a fun feature, I think. But I still think it's got more in common with bullet time than anything else.
I think there's more than one way to skin a cat. My preference is for a focus on character skill. But not doing so only makes it a different type of RPG, I think. I mean hell, even tabletop gaming has it's own factions and opinions on what constitutes a "pure" tabletop RPG. (White Wolf's old World of Darkness system for example was streamlined specifically so as to not get in the way or narrative and to focus more on roleplaying than rules. Whereas something like GURPS took the approach that by attempting to simulate and abstract as many variables for as many situations as possible you supported the narratives and possible roleplaying opportunities by leaving as little up to guess-work as possible.)
Anyway, I think there's plenty of room for a real-time game to allow character skill to influence outcomes and combat. The question is whether or not that's going to happen in Fallout 4.