I feel like SpacemanSpiff. Anytime you can affect the derived stats, you should go for it. It really impacts your game.
Well some of them are simply not -THAT- crucial.
STR, unless you aim to use every single weapon possible, isn't in high demand. With a starting STR of 5, you can effectively get the maximum of 10 STR with the proper quests completed, the implant and the strength implant.
Perception as a stat is made practically obsolete by a certain companion. It still has powerful perks tied to it, but once you have 6 perception then you're pretty much set.
Endurance you can always use more of.
Charisma isn't super important; it's a luxury.
Intelligence isn't super important; with 4 INT you can still max many of your skills.
Agility you can always use more of. Faster reload speed.
Luck you can always use more of. Increases your odds at the casinos (free money) and your crit increases your damage output.
So Endurance, Luck and Agility are really the only ones that seem to constantly add direct benefit.
Besides, as I said there's several powerful perks, and Intense Training sort of kills replay value imo; it makes characters feel same-y. Overall though, there's definitely perks that trump Intense training spam. For example, instead of adding a point to agility, Rapid Reload is a bigger bonus, as is Action Boy. Instead of adding a point to Endurance, Life Giver provides a bigger bonus. Instead of adding a point to Luck, Finesse is a far greater bonus. Thus, as I originally said, Intense training is a perk best saved for unlocking other perks your character otherwise doesn't have access to.