Although id love to see some english city, birmingham manchester or london perhaps, after the great war. It isnt really plausable, we have no evidence (that i can recall) which tells us that vault tec existed outside of america, and the heart of fallout seems to be the Vaults, without them, its just not the same to me. So with that in mind, i would like to see New york, huge vaults underneath the statue or liberty? empire state building etc? that would rock, it would be very Guerella as far as combat goes aswell.
I'm not a person to sugar coat things so here's what I have to say. There is as much chance of Fallout getting a sequel as there is gamesas making Elder Scrolls 5. Don't get me wrong, I do think gamesas will make an Elder Scrolls 5. However if Oblivion is the last Elder Scrolls game then they can end it without having a whole bunch of loose ends to tie up. Yeah there are a bunch of Dedric princes still alive but that doesn't mean they will try to destroy the world like Dagon. There was a hint a there being an Elder Scrolls 5 at the end of Oblivion. Now, they can end the Fallout series and not make another one, because the world changes in all ending and in one ending *Spoiler Alert* The Mutants along with all of the other infected are killed by the modified FEV put into the water. gamesas could easily say the series is over because of that ending. If they make another one it will probably be along the same lines as Fallout 3 and based off the ending they choose. It could very well be about making the water drinkable on the west coast based off the designs of the Project Purity from FO3. It could also be about finishing out the mutants once and for all using the water containing the modified FEV. Either way you go, Elder Scroll 5 will most likely be made first (If they make it). Unless they make FO4 on the same system and hold ES5 for newer technology. I would like to see it moved back somewhere in the west coast back to the roots if and when they do make a sequel.
What? loose ends? are you KIDDING, they have gold to work with, without an emperor the empire will fall into decline and face rebelion from every province, that for me would be great, and Dagon isnt dead, daedra cant die. And not all daedra are intent on invading tamriel either.
Besides, as far as the FEV goes, they could say it didnt work, or it could take years to effect mutants, or that it even had a reverse effect and created a new strain of mutant.