This is extreme speculation.
Consider, however, the prospect that you could have been woken from cryogenic stasis before, explored the wasteland, returned, and had your memory of all those experiences erased?
The Memory Den would then, perhaps, have a whole new spin and element to it.
Your character could then plausibly encounter NPCs that seem to know you, that you (currently) have no memory of.
The effects of previous adventures (now forgotten) might now come back to haunt, or help you.
Perhaps the last time you left Vault 111, you left with your child and spouse, but, for whatever reason were compelled to return to Vault 111, and now don't remember?
It's something to think about.
Thoughts?